The Future of Humanity: Advancements in Editing Human DNA

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Although we are all different and unique, we humans have 99.9% of the same genetic blueprint (blue print) to the extent that the deoxyribonucleic acid or DNA of Chimpanzees is 98% identical to the DNA of humans. But that difference of two percent makes it Chimpanzees and us humans. This difference of 0.01 percent separates all of us humans from each other. This 0.01 percent is a small difference that is the most important that gives each human a unique identity. It usually decides how you will stand out from others, what qualities you will have and what diseases you may have. Our DNA is a secret but can it and the genes in it be changed so that we can change ourselves in the future or avoid new diseases in the future.

All of our bodies are made up of cells and a normal human being has about 15 billion cells and they can increase or decrease depending on the weight of each person. The most important part of our cell is the nucleus. If it is said in simple words, the central part of the cell is called the nucleus and inside this central part there are 23 pairs of chromosomes, meaning their total number is 46. Each of these 23 lone pairs contains one chromosome from the mother and one from the father. These chromosomes are the storage places of our genetic codes, meaning each chromosome contains our genetic code and the name of this code is DNA. Just as everything in the computer is made with coding, similarly our body is made on this coding called DNA. When each cell of the body dies, its information is transferred to a new cell by DNA. Our genetic blueprint is actually stored in this DNA. DNA transmits this information about our genetic makeup from one generation to the next. Simply put, our DNA carries our genetic information, which is why a human child is a human being. A person's appearance, color, thoughts, understanding, all this is transferred from one generation to another with the help of his DNA. Many diseases are also genetic which are caused by DNA. That DNA is actually coiled in a twisted form. If you were to extract the DNA from a single organism and pull it apart, it would be 6 feet long but only 50 billionths of an inch thick. If you were to pull all the DNA in your body and connect it to each other, a line would be so long that it would reach from the Earth to the Sun 600 times. Like their DNA, our body has ribonucleic acid or RNA that makes proteins in our body, and the chain of DNA doubles while that of RNA is single.

Why is DNA so important?

Ever since this world was formed, every living thing, every bacterium, we humans are fighting for our survival and the changes that come in us with this fight are what we learn from them or the mutation that takes place. It is passed on to the next generations with the help of evolution and the DNA of the previous generations transmits the same information to the next generations and because of that we are like our parents, their color, the color of their eyes, their skills, we inherit them. But when there is some kind of defect in DNA, it is called the process of change (mutate) and this change can be good or bad. Due to this change one's body can change a human hand has six fingers, and a child's hair is white at birth, these are all due to changes. Mutations in humans don't make much of a difference, but when a virus or bacteria mutates, it can become much more dangerous or much weaker. Sometimes a change in an organism or in us humans is passed down to the next generation.

Can we make modifications to our DNA to make our future generations stronger, better?

Genetic engineers are researching this. Some genetic diseases with physical ability or information about it are also transmitted to the next generation with the help of DNA and according to a survey, one out of every 25 children is born with some genetic defect. But if we recognize these genetic defects in time and somehow, we can genetically modify them, then we can prevent many infectious diseases from reaching the next generation. This procedure is called gene editing. Scientists are doing a lot of research on this project as hybrids of many agricultural species are created by genetic modification. Apart from that, biologists are developing many next-generation antibiotics that can fight even the most dangerous infectious diseases. Many countries of the world are also researching genetic modification to strengthen their military so that in the future they can produce people who can work longer without getting tired and who are stronger than us. One of the main difficulties in working on this project is that scientists need to be very careful. If even the smallest mistake is made in the DNA or genetic mutation, it can make a person completely different. And for this, scientists have proposed a new theory according to which a person's damaged organs are repaired or replaced. This machine is called CRISPR-Cas9. On which research is being done in the United States. In this procedure, scientists replace the damaged part of the DNA in the body and repair it in some places. This is also called genome editing. Thus, many infectious diseases can be cured with the help of genome editing. However, in 2015, for the first time, this technique has been used on humans. A little girl in the UK had cancer for which there is no cure, and a blood sample was taken and genome-editing genes were inserted into her blood, similar to fresh DNA. Then these genome-edited organisms stopped the growth of cancer cells and thus did the trick.

Even today this craft is used to get rid of infectious diseases. But this profession requires a lot of observation and everything should be perfect in it, there should not be any possibility of confusion. Maybe in the future we will make genetic modifications in our DNA and become a superhuman who is safe from all kinds of diseases.


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